Formulation and evaluation of oral reconstitutable. The suspensions were then evaluated for the ph, viscosity, sedimentation volume, redispersibility, antacid and antiulcer activity. Avipattikar suspension was reconstituted and evaluated by method described in section 2. The mixture of magnesium and aluminium hydroxide is used as the model antacid. Evaluation of antacid suspensions containing aluminum. Effects of magnesiumaluminum hydroxide antacid on absorption of. Sudeendra bhat 2 and murthy sudarshan dakshina 2 1 sarada vilas college of pharmacy, mysore india. Formulation and evaluation of an antacid and antiulcer. Hem sl, white jl, buehler jd, luber jr, grim wm, lipka ea. Prepared formulations wereevaluated by uv system in. Another action of antacids is to prevent the conversion of gastric pepsinogen to pepsin, the active form.
Pdf antacids have been widely used in the treatment of various gastric and duodenal disorders such as heartburn, reflux esophagitis, gastritis. Pdf formulation and evaluation of sustained and raft. Formulation and evaluation of an antacid and antiulcer suspension containing herbal drugs g. Evaluation of raftformingantacid neutralizing capacity. Chewable tablets should be masticated and swallowed at once, with a drink of water. Maalox was used in its liquid formulation rhonepoulenc. This is a proteolytic enzyme thought to mediate tissue injury in ulcer disease. Three conceptually different titration procedures are used to evaluate the performance of several antacid suspension products. Liquid antacid suspensions containing aluminum hydroxide and magnesium hydroxide were evaluated for composition, antacid properties, and product quality. How to use antacid 200 mg200 mg20 mg5 ml oral suspension. It is poorly soluble in the water and hence the formulation is in the form of an effervescent tablet so that the disintegration time of the drug is not hindering the action. Evaluation of antacid suspensions containing aluminum hydroxide.
Evaluation of antacid suspensions containing aluminum hydroxide and magnesium hydroxide. The formulation of antacid products in suspension is a. Follow all the directions on the product package or use as. The antacid tablets are also used by selfmedication for the treatment of a wide variety of gastric symptoms1. Evaluation of raftforming antacid neutralizing capacity. Antacids have been widely used in the treatment of various gastric and duodenal disorders such as heartburn, reflux esophagitis, gastritis, irritable stomach, gastric and duodenal ulcers. Antacid 200 mg200 mg20 mg5 ml oral suspension webmd. The continuous or semisolid or external phase and internal. Formulation and evaluation of sustained and raft forming antacid tablet. Take this medication by mouth, usually after meals and at bedtime as needed.